Chadine's E-portfolio
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Hey, I’m Chadine.
I am a Biomedical Engineering student at the University of Florida, with interest in the field of tissue engineering and regenerative medicine. On my free time, I enjoying playing soccer and painting!
My Project
Extracellular Vesicle Stability Study
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PI name: Dr.Taylor
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Department: J. Crayton Pruitt Family Department of Biomedical Engineering
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Duration of project affiliation: One year
Research Focus and Project Responsibilities
Extracellular vesicles (EVs) hold great promise for improved cell-free therapies due to their role in intercellular communication and their ability to carry and deliver various biomolecules, including lipids, DNA, RNA, proteins, and glycans, which serve as biomarkers in different physiological and pathological states. This makes EVs promising candidates for targeted drug delivery, gene therapy, and immunotherapy. EVs also have limited adverse effects when used for therapeutic purposes since they are composed of cell-derived materials and are studied for their potential for targeted cell delivery. Examples of areas of research include cancer, cardiovascular disease, neurovegetative disorders, and wound healing. Despite the significant advances in recent years, the key issue with EV research remains storage stability. The storage capacity of EVs depends on multiple factors including their size, temperature of storage, duration of storage, and freeze-thaw cycles. Here, we evaluate the stability and functionality of EVs in different storage conditions at different time points. The results of this study can fill in the knowledge gaps and give us insight to the most optimal storage conditions for EVs to maximize their shelf life and usability for cell-free therapy research across many different clinical areas.
Relevant Coursework in Biomedical Engineering
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Biomedical Instrumentations
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Biomedical FundamentalsEngineering mechanics: Statics
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Biosignals and Systems
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Computer Applications for BME
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Clinically-Inspired Engineering Design
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Biomedical Materials
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Molecular Biomedical Engineering
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Cellular Engineering Laboratory